Publications

John Blazeck

  • Triplett, T., Garrison, K., Marshall, N., Donkor, M., Blazeck, J., Lamb, C., Qerqez, A., Tano, Y., Lu, W.-C., Karamitros, C., Ford, K., Tan, B., Zhang, M., Kumada, Y., Yemeny, M.S., Sentandreu, E., Fromm, G., Tiziani, S., Schreiber, T. H., Manfredi, M., Ehrlich, L. I. R., Stone, E., and Georgiou, G. (2018) Reversal of indolemine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme. Nature Biotech, 36:758–764.

Julie Champion

  • Tsoras AN, Champion JA. 2018.Cross-linked peptide nanoclusters for delivery of oncofetal antigen as a cancer vaccine. Bioconjug Chem. Mar 21;29(3):776-785. doi: 10.1021/acs.bioconjchem.8b00079. Epub 2018 Feb 13. PubMed PMID: 29436221. 
  • Herrera, EL, Padmore, TJ, Champion, JA. 2016. Bacterial effector nanoparticles as breast cancer therapeutics. Mol Pharm. 13(3):710-9. doi: 10.1021/acs.molpharmaceut.5b00377. Epub 2016 Jan 22. PMID: 26800341
  • Garapaty A, Champion JA. 2015. Biomimetic and synthetic interfaces to tune immune responses.Biointerphases. 10(3):030801. doi: 10.1116/1.4922798.  PMID: 26178262

Tim Cope

  • Wang AB, Housley SN, Flores AM, Kircher SM, Perreault EJ, Cope TC. A review of movement disorders in chemotherapy-induced neurotoxicity. J Neuroeng Rehabil. 2021 Jan 25;18(1):16. doi: 10.1186/s12984-021-00818-2. PMID: 33494755; PMCID: PMC7836454.
  • Housley SN, Nardelli P, Carrasco DI, Rotterman TM, Pfahl E, Matyunina LV, McDonald JF, Cope TC. Cancer Exacerbates Chemotherapy-Induced Sensory Neuropathy. Cancer Res. 2020 Jul 1;80(13):2940-2955. doi: 10.1158/0008-5472.CAN-19-2331. Epub 2020 Apr 28. PMID: 32345673; PMCID: PMC7340531.
  • Housley SN, Nardelli P, Rotterman TM, Cope TC. Neural circuit mechanisms of sensorimotor disability in cancer treatment. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2100428118. doi: 10.1073/pnas.2100428118. PMID: 34911753; PMCID: PMC8713769.

James Dahlman

  • Paunovska, Kalina et al. Drug delivery systems for RNA therapeutics. Nature reviews. Genetics, 1–16. 4 Jan. 2022, doi:10.1038/s41576-021-00439-4 

Michelle Dawson

  • McAndrews KM, McGrail DJ, Ravikumar N, Dawson MR. 2015. Mesenchymal stem cells induce directional migration of invasive breast cancer cells through TGF-β. Sci Rep. 5:16941. doi: 10.1038/srep16941. PMID:26585689
  • McGrail DJ, McAndrews KM, Brandenburg CP, Ravikumar N, Kieu QM, Dawson MR. 2015. Osmotic regulation is required for cancer cell survival under solid stress. Biophys J. 109(7):1334-7. doi: 10.1016/j.bpj.2015.07.046.PMID:26445434
  • McAndrews KM, Yi J, McGrail DJ, Dawson MR. 2015. Enhanced adhesion of stromal cells to invasive cancer cells regulated by cadherin 11. ACS Chem Biol. 10(8):1932-8. doi: 10.1021/acschembio.5b00353. Epub 2015 Jun 17.PMID:26046821
  • McGrail DJ, Khambhati NN, Qi MX, Patel KS, Ravikumar N, Brandenburg CP, Dawson MR. 2015. Alterations in ovarian cancer cell adhesion drive taxol resistance by increasing microtubule dynamics in a FAK-dependent manner. Sci Rep. 5:9529. doi: 10.1038/srep09529. PMID:25886093
  • McGrail DJ, Kieu QM, Iandoli JA, Dawson MR. 2015. Actomyosin tension as a determinant of metastatic cancer mechanical tropism. Phys Biol. 12(2):026001. doi: 10.1088/1478-3975/12/2/026001. PMID:25706686
  • McGrail DJ, Mezencev R, Kieu QM, McDonald JF, Dawson MR. 2015.  SNAIL-induced epithelial-to-mesenchymal transition produces concerted biophysical changes from altered cytoskeletal gene expression. FASEB J. 29(4):1280-9. doi: 10.1096/fj.14-257345. Epub 2014 Dec 9. PMID:25491311

Jaydev Desai

  • Kihan Park, Wenjin Chen, Marina A. Chekmareva, David J. Foran, and Jaydev P. Desai, Electromechanical Coupling Factor of Breast Tissue as a Biomarker for Breast Cancer, IEEE Transactions on Biomedical Engineering, vol. 65, no. 1, pp. 96-103, Jan. 2018; DOI: 10.1109/TBME.2017.2695103.
  • Hardik J. Pandya, Rajarshi Roy, Kihan Park, and Jaydev P. Desai, Microscale Sensors for Breast Cancer Diagnosis, Chapter 13 in Encyclopedia of Medical Robotics – Volume 2: Micro and  Nano Robotics in Medicine, pp. 275-310, World Scientific, 2018; DOI: 10.1142/9789813232280_0013; ISBN: 978-9813232228.

J. Brandon Dixon

  • Binkley, J., Weiler, M., Frank, N., Bober, L., Dixon, J. B., and Stratford, P. W., Reliability and convergent validity of the LymphaTech system to asses arm volume in patients during and after treatment for breast cancer. Physical Therapy, in press, 2019.
  • Lu, I. M. and Dixon, J. B., Assessment of upper-extremity swelling among breast cancer survivors with a commercial infrared sensor Lymphatic Research and Biology, 17(4), 424-433, 2019.
     

Mostafa A. El Sayed

  • Deinavizadeh, Maryam, Kiasat, Alireza, Hooshmand, Nasrin, Shafiei, Mohammad, Sabaeian, Mohammad, Mirzajani, Roya, Zahraei, Seyed Mohammadsaleh, Labouta, Hagar I. and El-Sayed, Mostafa A.. Smart NIR-light and pH responsive doxorubicin-loaded GNRs@SBA-15-SH nanocomposite for chemo-photothermal therapy of cancer Nanophotonics, vol. 10, no. 12, 2021, pp. 3303-3319. 
  • Erik C Dreaden, Mostafa A El-Sayed. 2021. Detecting and destroying cancer cells in more than one way with noble metals and different confinement properties on the nanoscale. In Nanomaterials and Neoplasms. Jenny Stanford Publishing. pp 1-29.
  • Aioub M, El-Sayed MA. 2016. A real-time surface enhanced raman spectroscopy study of plasmonic photothermal cell death using targeted gold nanoparticles. J Am Chem Soc. 138(4):1258-64. doi: 10.1021/jacs.5b10997. Epub 2016 Jan 25.PMID:26746480
  • El-Sayed MA. 2014. Concluding remarks: summary of some of our recent studies in the field of conjugating plasmonic gold nanoparticles to single cancer cells and their molecular and cellular dynamics. Faraday Discuss. 175:305-8. doi: 10.1039/c4fd00213j. PMID:25588759
  • Panikkanvalappil SR, Hira SM, Mahmoud MA, El-Sayed MA. 2014. Unraveling the biomolecular snapshots of mitosis in healthy and cancer cells using plasmonically-enhanced Raman spectroscopy. J Am Chem Soc. 136(45):15961-8. doi: 10.1021/ja506289u. Epub 2014 Nov 3. PMID:25330058
  • Kang B, Austin LA, El-Sayed MA. 2014. Observing real-time molecular event dynamics of apoptosis in living cancer cells using nuclear-targeted plasmonically enhanced Raman nanoprobes. ACS Nano. 8(5):4883-92. doi: 10.1021/nn500840x. Epub 2014 Apr 18. PMID:24708404
  • Ali MR, Panikkanvalappil SR, El-Sayed MA. 2014. Enhancing the efficiency of gold nanoparticles treatment of cancer by increasing their rate of endocytosis and cell accumulation using rifampicin. J Am Chem Soc. 136(12):4464-7. doi: 10.1021/ja4124412. Epub 2014 Mar 12. PMID:24467386

Stas Emelianov

  • M.K. Laffey, K.P. Kubelick, E.M. Donnelly, S.Y. Emelianov, Effects of freezing on mesenchymal stem cells labeled with gold nanoparticles, Tissue Engineering, Part C: Methods, 26(1):1-10 (2020).
  • D.S. Dumani, I.-C. Sun, S.Y. Emelianov, Ultrasound-guided immunofunctional photoacoustic imaging for diagnosis of lymph node metastases, Nanoscale, 11, 11649 – 11659, DOI: 10.1039/C9NR02920F (2019)
  • Facundo Fernandez
  • Bifarin OO, Gaul DA, Sah S, Arnold RS, Ogan K, Master VA, Roberts DL, Bergquist SH, Petros JA, Edison AS, Fernández FM. Urine-based metabolomics and machine learning reveals metabolites associated with renal cell carcinoma stage. Cancers. 2021; 13(24):6253. https://doi.org/10.3390/cancers13246253 
  • Kim, O, Park, EY, Kwon SY, et al. 2020. Targeting progesterone signaling prevents metastatic ovarian cancer. PNAS, USA 117:31993-32004.

Yuhong Fan

  • Medrzycki M, Zhang Y, Zhang W, Cao K, Pan C, Lailler N, McDonald JF, Bouhassira EE, Fan Y.2014. Histone h1.3 suppresses h19 noncoding RNA expression and cell growth of ovarian cancer cells.Cancer Res. 74(22):6463-73. doi: 10.1158/0008-5472.CAN-13-2922. Epub 2014 Sep 9. PMID:25205099

Facundo Fernandez

  • Jones CM, Monge ME, Kim J, Matzuk MM, Fernández FM. 2015. Metabolomic serum profiling detects early-stage high-grade serous ovarian cancer in a mouse model. J Proteome Res. 14(2):917-27. doi: 10.1021/pr5009948. Epub 2015 Jan 16. PMID:25567202
  • Zang X, Jones CM, Long TQ, Monge ME, Zhou M, Walker LD, Mezencev R, Gray A, McDonald JF, Fernández FM.  2014. Feasibility of detecting prostate cancer by ultraperformance liquid chromatography-mass spectrometry serum metabolomics. J Proteome Res. 13(7):3444-54. doi: 10.1021/pr500409q. Epub 2014 Jun 25. PMID:24922590

Greg Gibson

  • Gibson G, Powell JE, Marigorta UM. 2015. Expression quantitative trait locus analysis for translational medicine.Genome Med. 7(1):60. doi: 10.1186/s13073-015-0186-7. eCollection 2015. PMID:26110023
  • Gibson G. 2014. Cancer: Directions for the drivers. Nature. 512(7512):31-2. doi: 10.1038/nature13649. Epub 2014 Jul 23. PMID:25079332

King Jordan

  • Lee, K. K., Rishishwar, L., Ban, D., Nagar, S. D., Mariño-Ramírez, L., McDonald, J. F., & Jordan, I. K. 2022. Association of genetic ancestry and molecular signatures with cancer survival disparities: a pan-cancer analysis. Cancer research. canres:CAN-21-2105-A.2021 
  • Clayton, E.A., Rishishwar, L., Huang, T-C., Gulati, S., Ban, D., McDonald, J.F., and Jordan, I.K. 2020. An atlas of transposable element derived alternative splicing in cancer.
  • Philos Trans R Soc Lond B Biol Sci. 375: 20190342.
  • Kuruc, J.C., Durant-Archibold, A.A., Motta, J., Rao, K.S., Trachtenberg, B., Ramos, C., Wang, H., Gorenstein, D., Vannberg, F., Jordan, I.K. 2019. Development of anthracycline-induced dilated cardiomyopathy due to mutation on LMNA gene in a breast cancer patient: a case report. BMC Cardiovasc Disord. 19: 169.
  • Clayton, E.A., Wang, L., Rishishwar, L., Wang, J., McDonald, J.F. and Jordan I.K., 2016. Patterns of transposable element expression and insertion in cancer. Front Mol Biosci. 3: 76.
  • Hu, B., Ying, X., Wang, J., Piriyapongsa, J., Jordan, I.K., Sheng, J., Yu, F., Zhao, P., Li, Y., Wang, H., Ng, W.L., Hu, S., Wang, X., Wang, C., Zheng, X., Li, W., Curran, W.J., and Wang, Y., 2014. Identification of a tumor suppressive human specific microRNA within the FHIT tumor suppressor gene. Cancer Res. 74: 2283-94
  • Niu P, Smagul A, Wang L, Sadvakas A, Sha Y, Pérez LM, Nussupbekova A, Amirbekov A, Akanov AA, Gálvez BG, Jordan IK, Lunyak VV. 2015. Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence. Oncotarget. 6(20):17938-57.PMID:26255627
  • Hu B, Ying X, Wang J, Piriyapongsa J, Jordan IK, Sheng J, Yu F, Zhao P, Li Y, Wang H, Ng WL, Hu S, Wang X, Wang C, Zheng X, Li W, Curran WJ, Wang Y. 2014.  Identification of a tumor-suppressive human-specific microRNA within the FHIT tumor-suppressor gene. Cancer Res. 74(8):2283-94. doi: 10.1158/0008-5472.CAN-13-3279. Epub 2014 Feb 20.PMID:24556720

Melissa Kemp

  • Shukla, K., Singh, N., Lewis, J.E., Tsang, A.W., Kemp, M., C.M. Furdui, MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy with Ionizing Radiation in Head and Neck Squamous Cell Cancer. Frontiers in Oncol, DOI: 10.3389/fonc.2020.536377;  2020.
  • Paudel B.B , Lewis J.E., Hardeman K.N., Hayford C.E. , Robbins C.J. , Codreanu G.S., Sherrod S.D., McLean J.A., Kemp M.L., Quaranta, V. Elevated Redox Capacity Confers Drug-Insensitivity to BRAF inhibitors in Melanoma. Cancer Research, DOI:  10.1158/0008-5472.CAN-19-3588, 2020.
  • Forshaw T.E., Holmila R., Nelson K.J., Lewis J.E., Kemp M.L., Tsang A.W., L Poole L.B., Lowther W.T., Furdui C.M. Peroxiredoxins in Cancer and Response to Radiation Therapies Antioxidants 8(1). pii: E11. 2019.
  • Chen, X., *Mims, J., Huang, X., Singh, N., Motea, E., Planchon-Pope, S.M., Beg, M., Tsang, A.W., Porosnicu, M., Kemp, M.L., Boothman, D.A., Furdui, C.A. Modulators of Redox Metabolism in Head and Neck Cancer. Antioxidants & Redox Signaling, doi: 10.1089/ars.2017.7423, 2017.
  • Prasanphanich AF, Arencibia CA, Kemp ML. 2014. Redox processes inform multivariate transdifferentiation trajectories associated with TGFβ-induced epithelial-mesenchymal transition. Free Radic Biol Med. 76:1-13. doi: 10.1016/j.freeradbiomed.2014.07.032. Epub 2014 Aug 1. PMID:25088330

Gabe Kwong

  • Cazanave SC, Warren AD, Pacula M, Touti F, Zagorska A, Gural N, Huang EK, Sherman S, Cheema M, Ibarra S, Serer A, Bates J, Billin AN, Liles JT, Budas GR, Breckenridge DG, Tiniakos D, Ratziu V, Daly AK, Govaere O, Anstee QM, Gelrud L, Luther J, Chung RT, Corey KE, Winckler W, Bhatia SN, and Kwong GA, Peptide-based urinary monitoring of fibrotic non-alcoholic steatohepatitis by mass barcoded activity-based sensors Sci. Transl. Med. 13, eabe8939 (2021). 
  • Miller IC†, Zamat A†, Sun LK, Phuengkham H, Harris AM, Gamboa L, Yang J, Murad JP, Priceman SJ and Kwong GA, Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control Nat. Biomed. Eng. 5, 1348–1359 (2021). 
  • Kwong GA‡, Ghosh S, Gamboa L, Patriotis C, Srivastava S‡, and Bhatia SN‡, Synthetic Biomarkers: A 21st century path to early cancer detection Nat. Rev. Cancer 21, 655–668 (2021). 
  • Kwong GA, Macrophage sensors for early cancer detection Clin. Chem. 66(2), 268–270 (2020).
  • Miller IC, Gamboa Castro M, Maenza J, Weis JP and Kwong GA, Remote control of mammalian cells with heat-triggered gene switches and photothermal pulse trains ACS Synth. Biol. 7(4), 1167–1173 (2018).

John McDonald

  • McDonald, JF (2021). The ability to accurately predict optimal drug therapies for cancer patients is rapidly approaching. Health Europa.
  • Lee, KK, Rishishwar, L, Ban, D, Nagar, SD, Marino-Ramirez, McDonald, JF, Jordan, IK. (2021). Effects of genetic ancestry and molecular signatures on cancer survival disparities: a pan-cancer analysis. Can. Res. (in press).
  • Arshad, Z and McDonald, JF. (2021). Changes in gene-gene interactions associated with cancer onset and progression are largely independent of changes in gene expression. iScience, 2021; 24 (12): 103522. https://doi.org/10.1016/
  • Lanka, J, Housley, SN, Benigno, BB and McDonald, JF. (2021). ELAF: An ensemble-based machine learning algorithm that predicts anti-cancer drug response with high accuracy. J. Oncol. Res. 4 (1): 1-11.https://escires.com/articles/JOR-4-111.pdf
  • Stone, N.E., Raj, A., Young, K.M. , DeLuca, A.P., Chrit, F.E., Tucker, B.A., Alexeev, A., McDonald J.F., Benigno, B.B., Sulchek, T. (2021). Label-free microfluidic enrichment of cancer cells from non-cancer cells in ascites. Sci Rep 11, 18032. https://doi.org/10.1038/s41598-021-96862-y.
  • Clayton, E. A., Pujol, T. A., McDonald, JF., Qiu, P (2020). Leveraging TCGA gene expression data to build predictive models for cancer drug response. BMC Bioinformatics. https://doi.org/10.1186/s12859-020-03690-4.
  • Housley, SN., Nardelli, P., Carrasco, D., Rotterman, TM., Pfahl, E., Matyunina, L., McDonald, JF., Cope, TC (2020). Cancer Exacerbates Chemotherapy-Induced Sensory Neuropathy. Cancer Res. https://doi.org/10.1158/0008-5472.CAN-19-2331.
  • Zhou, H., Cao, H., Matyunina, L., Shelby, M., Cassels, L., McDonald, JF., & Skolnick, J. (2020). MEDICASCY: A Machine Learning Approach for Predicting Small-Molecule Drug Side Effects, Indications, Efficacy, and Modes of Action. Mol. Pharmaceutics. https://doi.org/10.1021/acs.molpharmaceut.9b01248.
  • Zhang, M., Wang, Y., Matyunina, L., Akbar, A., McDonald, JF. (2020). The ability of miRNAs to induce mesenchymal-to-epithelial transition (MET) in cancer cells is highly dependent upon genetic background. Cancer Letters, 480, 15-23. DOI:10.1016/j.canlet.2020.03.023.
  • Clayton, E. A., Rishishwar, L., Huang, T. C., Gulati, S., Ban, D., McDonald, J. F., & Jordan, I. K. (2020). An atlas of transposable element-derived alternative splicing in cancer. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 375(1795), 20190342.
  • Clayton, E. A., Khalid, S., Ban, D., Wang, L., Jordan, I. K., & McDonald, J. F. (2020). Tumor suppressor genes and allele-specific expression: mechanisms and significance. Oncotarget, 11(4), 462.
  • Birmingham, KG., O’Melia, MJ., Ban, D., Mouw, J., Edwards, EE., Marcus, AI., McDonald, JF., Thomas SN. 2019. Analyzing Mechanisms of Metastatic Cancer Cell Adhesive Phenotype Leveraging Preparative Adhesion Chromatography Microfluidic. Advanced biosystems, 3(3), 1800328. DOI:10.1002/adbi.201800328.
  • Lopes, E., Paim, L. R., Matos-Souza, J. R., Calegari, D. R., Gorla, J. I., Cliquet, A., Jr, … Schreiber, R. 2019. Bioinformatics analysis of circulating miRNAs related to cancer following spinal cord injury. Bioscience reports, 39(9), BSR20190989. DOI:10.1042/BSR20190989.
  • Chu, CH., Liu, R., Ozkaya-Ahmadov, T., Boya, M., Swain, BE., Owens, JM., Burentugs, E., Bilen, MA., McDonald, JF., Sarioglu, AF. 2019. Hybrid negative enrichment of circulating tumor cells from whole blood in a 3D-printed monolithic device. Lab Chip, 20, 3427-3437. DOI:10.1039/c9lc00575g.
  • Lopes, E., Paim, L. R., Matos-Souza, J. R., Calegari, D. R., Gorla, J. I., Cliquet, A., Jr, … Schreiber, R. 2019. Bioinformatics analysis of circulating miRNAs related to cancer following spinal cord injury. Bioscience reports, 39(9), BSR20190989. DOI:10.1042/BSR20190989.
  • Zhang, M., Jabbari, N., Satpathy, M., Matyunina, L. V., Wang, Y., McDonald, L. D., & McDonald, J. F. 2019. Sequence diverse miRNAs converge to induce mesenchymal-to-epithelial transition in ovarian cancer cells through direct and indirect regulatory controls. Cancer letters, 449, 168-175. DOI: 10.1016/j.canlet.2019.05.039.
  • Elliott, B., Millena, A. C., Matyunina, L., Zhang, M., Zou, J., Wang, G., Zhang, Q., Bowen, N., Eaton, V., Webb, G., Thompson, S., McDonald JF., Khan, S. 2019. Essential role of JunD in cell proliferation is mediated via MYC signaling in prostate cancer cells. Cancer letters, 448, 155-167. DOI: 10.1016/j.canlet.2019.02.005.
  • Adegboyega Oyelere
  • GG Faura, B Wu, AK Oyelere, S France. 2022. Synthetic methodology-enable discovery of a tunable indole template for COX-1 inhibition and anti-cancer activity. Bioorganic & Med Chem. 57:116633.
  • Wu, B.; Sodji, Q.H.; Oyelere, A.K. Inflammation, Fibrosis and Cancer: Mechanisms,
  • Therapeutic Options and Challenges. Cancers 2022, 14, 552.
  • https://doi.org/10.3390/cancers14030552.
  • Tapadar S, Fathi S, Wu B, Sun CQ, Raji I, Moore SG, Arnold RS, Gaul DA, Petros JA, Oyelere AK. Liver-Targeting Class I Selective Histone Deacetylase Inhibitors Potently Suppress Hepatocellular Tumor Growth as Standalone Agents. Cancers. 2020; 12(11):3095. https://doi.org/10.3390/cancers12113095 
  • Caggia S, Tapadar S, Wu B, Venugopal SV, Garrett AS, Kumar A, Stiffend JS, Davis JS, Oyelere AK, Khan SA. Small Molecule Inhibitors Targeting Gαi2 Protein Attenuate Migration of Cancer Cells. Cancers. 2020; 12(6):1631. https://doi.org/10.3390/cancers1206163.
  • B. Wu, S. Fathi, S. Mortley, M. Mohiuddin, Y.C. Jang, A.K. Oyelere
  • Pyrimethamine conjugated histone deacetylase inhibitors: design, synthesis and evidence for triple negative breast cancer selective cytotoxicity. Bioorg. Med. Chem., 28 (2020), p. 115345
  • Caggia S, Tapadar S, Wu B, Venugopal SV, Garrett AS, Kumar A, Stiffend JS, Davis JS, Oyelere AK, Khan SA. Small Molecule Inhibitors Targeting Gαi2 Protein Attenuate Migration of Cancer Cells. Cancers. 2020; 12(6):1631. https://doi.org/10.3390/cancers12061631.
  • Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity.Mezencev R, Matyunina LV, Jabbari N, McDonald JF.BMC Cancer. 2016 Mar 18.
  • Highly-accurate metabolomic detection of early-stage ovarian cancer.Gaul DA, Mezencev R, Long TQ, Jones CM, Benigno BB, Gray A, Fernández FM, McDonald JF.Sci Rep. 2015 Nov 17.
  • Integrated sequence and expression analysis of ovarian cancer structural variants underscores the importance of gene fusion regulation.Mittal VK, McDonald JF.BMC Med Genomics. 2015 Jul 17
  • Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles. Sengupta A, Mezencev R, McDonald JF, Prausnitz MR.Nanomedicine (Lond). 2015
  • Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids.Sodji QH, Kornacki JR, McDonald JF, Mrksich M, Oyelere AK.Eur J Med Chem. 2015
  • OVCAR-3 spheroid-derived cells display distinct metabolic profiles.Vermeersch KA, Wang L, Mezencev R, McDonald JF, Styczynski MP.PLoS One. 2015 Feb 17
  • Clinical selection criteria can predict futile intervention in patients referred for percutaneous endoscopic gastrostomy insertion.Holt DQ, McDonald JF, Murray ML, Hair C, Devonshire DA, Strauss BJ, Moore GT. Intern Med J. 2015 Jun

Alfred Merrill

  • Park WJ, Brenner O, Kogot-Levin A, Saada A, Merrill AH Jr, Pewzner-Jung Y, Futerman AH. 2015. Development of pheochromocytoma in ceramide synthase 2 null mice. Endocr Relat Cancer. 22(4):623-32. doi: 10.1530/ERC-15-0058. Epub 2015 Jun 25. PMID:26113602

Adegboyega Oyelere

  • Tapadar S, Fathi S, Raji I, Omesiete W, Kornacki JR, Mwakwari SC, Miyata M, Mitsutake K, Li JD, Mrksich M, Oyelere AK. 2015. A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities. Bioorg Med Chem. 23(24):7543-64. doi: 10.1016/j.bmc.2015.10.045. Epub 2015 Nov 2. PMID:26585275
  • Washington AZ, Tapadar S, George A, Oyelere AK. 2015.  Exploiting translational stalling peptides in an effort to extend azithromycin interaction within the prokaryotic ribosome nascent peptide exit tunnel. Bioorg Med Chem. 23(16):5198-209. doi: 10.1016/j.bmc.2015.04.078. Epub 2015 May 6. PMID:26037612
  • Sodji QH, Kornacki JR, McDonald JF, Mrksich M, Oyelere AK. 2015. Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids. Eur J Med Chem. 2015;96:340-59. doi: 10.1016/j.ejmech.2015.04.014. Epub 2015 Apr 8. PMID:25899338

Manu Platt

  • Schwartz AD, Adusei A, Tsegaye S, Moskaluk CA, Schneider SS, Platt MO, Seifu D, Peyton SR, Babbitt CC. Genetic Mutations Associated with Hormone-Positive Breast Cancer in a Small Cohort of Ethiopian Women. Annals of Biomedical Engineering . 2021 Aug;49(8):1900-1908. PMID: 34142276. 
  • Tumor cell-organized fibronectin maintenance of a dormant breast cancer population. 
  • Barney LE, Hall CL, Schwartz AD, Parks AN, Sparages C, Galarza S, Platt MO, Mercurio AM, Peyton SR. Science Advances 2020 Mar 11;6(11):eaaz4157. doi: 10.1126/sciadv.aaz4157. eCollection 2020 Mar. PMID: 32195352 .
  • Dynamic Model of Protease State and Inhibitor Trafficking to Predict Protease Activity in Breast Cancer Cells. 
  • Shockey WA, Kieslich CA, Wilder CL, Watson V, Platt MO Cell Mol Bioeng 2019 Jun 19;12(4):275-288. doi: 10.1007/s12195-019-00580-5. eCollection 2019 Aug. PMID: 31719914
  • Differential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cells.
  • Wilder CL, Walton C, Watson V, Stewart FA, Johnson J, Peyton SR, Payne CK, Odero-Marah V, Platt MO. Int J Biochem Cell Biol. 2016 Oct;79:199-208. doi: 10.1016/j.biocel.2016.08.030.
  • Park KY, Li G, Platt MO. 2015. Monocyte-derived macrophage assisted breast cancer cell invasion as a personalized, predictive metric to score metastatic risk. Sci Rep. 5:13855. doi: 10.1038/srep13855. PMID:26349896
  • Burton LJ, Smith BA, Smith BN, Loyd Q, Nagappan P, McKeithen D, Wilder CL, Platt MO, Hudson T, Odero-Marah VA.2015. Muscadine grape skin extract can antagonize Snail-cathepsin L-mediated invasion, migration and osteoclastogenesis in prostate and breast cancer cells. Carcinogenesis. 36(9):1019-27. doi: 10.1093/carcin/bgv084. Epub 2015 Jun 10. PMID:26069256

Mark Prausnitz

  • MJ Uddin, N Scoutaris, P Klepetsanis, B Chowdry, MR Prausnitz, D Douroumis (2015) Inkjet printing of transdermal microneedles for the delivery of anticancer agents, International Journal of Pharmaceutics, 494:593-602. 
  • Chakravarty P, Lane CD, Orlando TM, Prausnitz MR. 2016. Parameters affecting intracellular delivery of molecules using laser-activated carbon nanoparticles. Nanomedicine. S1549-9634(16)00004-6. doi: 10.1016/j.nano.2015.12.380. Epub ahead of print. PMID:26772422
  • Sengupta A, Mezencev R, McDonald JF, Prausnitz MR. 2015. Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles. Nanomedicine (Lond). 10(11):1775-84. doi: 10.2217/nnm.15.27. PMID:26080699

Francisco Robles

  • S. Soltani, A. Ojaghi, H. Qiao, N. Kaza, X. Li, Q. Dai, A. O. Osunkoya, F. E. Robles*, Prostate cancer histopathology with label-free multispectral deep UV microscopy quantifies phenotypes of tumor grade and aggressiveness, in review.
  • Soheil Soltani, Zhe Guang, Zhaobin Zhang, Jeffrey J Olson, Francisco E Robles. 2021. Label-free detection of brain tumors in a 9L gliosarcoma rat model using stimulated Raman scattering-spectroscopic optical coherence tomography. J Biomed Optics 26:76004.
  • P. Casteleiro Costa, Z. Guang, P. Ledwig, Z.  Zhang, S. Neill, J. J. Olson, F.E. Robles. Towards in-vivo label-free detction of brain tumor margins with epi-illumination tomographic quantitative phase imaging. Biomedical Optics Express 12 (3), 1621-1634, 2021. 

Philip Santangelo

  • Blanchard, E. L., Argyropoulou, D., Zurla, C., Bhosle, S. M., Vanover, D. & Santangelo, P. J. Quantification and Localization of Protein-RNA Interactions in Patient-Derived Archival Tumor Tissue. Cancer Res 79, 5418–5431 (2019).
  • Zurla, C., Jung, J. & Santangelo, P. J. Can we observe changes in mRNA ‘state’? Overview of methods to study mRNA interactions with regulatory proteins relevant in cancer related processes. Analyst 141, 548–562 (2016).
  • Roller BT, Munson JM, Brahma B, Santangelo PJ, Pai SB, Bellamkonda RV. 2015. Evans blue nanocarriers visually demarcate margins of invasive gliomas. Drug Deliv Transl Res. 5(2):116-24. doi: 10.1007/s13346-013-0139-x.PMID:25787737

Fatih Sarioglu

  • R. Oklu, R. Sheth, H. Albadawi, I. Bhan, A. F. Sarioglu, M. Choz, M. Zeinali, V. Deshpande, S. Maheswaran, D. A. Haber, S. L. Stott, A. X. Zhu, L. Goyal, M. Toner and D. T. Ting, Relationship between hepatocellular carcinoma circulating tumor cells and tumor volume Cancer Convergence, 2, 2 (2018).
    Liu R, Wang N, Kamili F, Sarioglu AF. 2016. Microfluidic CODES: a scalable multiplexed electronic sensor for orthogonal detection of particles in microfluidic channels. Lab Chip. 16(8):1350-7. doi: 10.1039/c6lc00209a. PMID:27021807
  • Kojić N, Milošević M, Petrović D, Isailović V, Sarioglu AF, Haber DA, Kojić M, Toner M. 2015. A computational study of circulating large tumor cells traversing microvessels. Comput Biol Med. 63:187-95. doi: 10.1016/j.compbiomed.2015.05.024. Epub 2015 Jun 10. PMID:26093786
  • Sarioglu AF, Aceto N, Kojic N, Donaldson MC, Zeinali M, Hamza B, Engstrom A, Zhu H, Sundaresan TK, Miyamoto DT, Luo X, Bardia A, Wittner BS, Ramaswamy S, Shioda T, Ting DT, Stott SL, Kapur R, Maheswaran S, Haber DA, Toner M. 2015. A microfluidic device for label-free, physical capture of circulating tumor cell clusters. Nat Methods. 12(7):685-91. doi: 10.1038/nmeth.3404. Epub 2015 May 18. PMID:25984697

Jeffrey Skolnick

  • Mitchel, J, Bajaj P, Patil K, Gunnarson A, Pourchet E, Kim Y, Skolnick J, Pai S B. 2021. Computational Identification of Stearic Acid as a Potential PDK1 Inhibitor and in vitro Validation of Stearic Acid as Colon Cancer Therapeutic in Combination with 5-Fluorouracil. Cancer Inform. 2021 Dec 13;20:11769351211065979. doi: 10.1177/11769351211065979.
  • Dhakshinamoorthy S, Dinh NT, Skolnick J, Styczynski MP. 2015. Metabolomics identifies the intersection of phosphoethanolamine with menaquinone-triggered apoptosis in an in vitro model of leukemia. Mol Biosyst. 2015 Sep;11(9):2406-16. doi: 10.1039/c5mb00237k. PMID:26175011

Mark Styczynski

  • Dhakshinamoorthy S, Dinh NT, Skolnick J, Styczynski MP. 2015. Metabolomics identifies the intersection of phosphoethanolamine with menaquinone-triggered apoptosis in an in vitro model of leukemia. Mol Biosyst. 11(9):2406-16. doi: 10.1039/c5mb00237k. PMID:26175011
  • Vermeersch KA, Wang L, Mezencev R, McDonald JF, Styczynski MP. 2015. OVCAR-3 spheroid-derived cells display distinct metabolic profiles. PLoS One. 10(2):e0118262. doi: 10.1371/journal.pone.0118262. eCollection 2015.PMID:25688563
  • Vermeersch KA, Wang L, McDonald JF, Styczynski MP. 2014.  Distinct metabolic responses of an ovarian cancer stem cell line. BMC Syst Biol. 2014 Dec 18;8:134. doi: 10.1186/s12918-014-0134-y. PMID:25518943

Todd Sulchek

  • Louise Kiru, Aimen Zlitni, Aidan Michael Tousley, Guillermo Nicolás Dalton, Wei Wu, Famyrah Lafortune, Anna Liu, Kristen May Cunanan, Hossein Nejadnik, Todd Sulchek, Michael Eugene Moseley, Robbie G Majzner, Heike Elisabeth Daldrup-Link. 2022. In vivo imaging of nanoparticle-labeled CAR T cells. Proc Natl Acad Sci 119:e2102363119.
  • Nicholas E Stone, Abhishek Raj, Katherine M Young, Adam P DeLuca, Fatima Ezahra Chrit, Budd A Tucker, Alexander Alexeev, John McDonald, Benedict B Benigno, Todd Sulchek. 2021. Label-free microfluidic enrichment of cancer cells from non-cancer cells in ascites. Sci Reports 11:1-9.

Susan Thomas

  • Francis, D.M., Manspeaker, M.P., Archer, P., Heiler, A., Sestito, L., Schudel, A., Thomas, S.N.§,2021. Drug-Eluting Immune Checkpoint Blockade Antibody-Nanoparticle Conjugate Enhances Locoregional and Systemic Combination Cancer Immunotherapy through T Lymphocyte Targeting. Biomaterials. Volume 279, 121184. 
  • O’Melia, M.J., Manspeaker, M.P., Thomas, S.N.§, 2021. Tumor-draining lymph nodes are survival niches that support CD8 T cell priming against lymphatic transported tumor antigen and therapeutic effects of immune checkpoint blockade in TNBC. Cancer Immunology, Immunotherapy. https://doi.org/10.1007/s00262-020-02792-5. 
  • Birmingham, K.G., O’Melia, M.J., Brody, S.¥, Reyes Aguilar, D.¥, El-Reyes, B., Lesinski, G., Thomas, S.N.§, 2020. Lymph node subcapsular sinus microenvironment-on-a-chip modeling shear flow relevant to lymphatic metastasis and immune cell homing. iScience. Volume 23, Issue 11, 101751.https://doi.org/10.1016/j.isci.2020.101751.
  • Manspeaker, M.P. and Thomas, S.N.§, 2020. Lymphatic immunomodulation using engineered drug delivery systems for cancer immunotherapy. Advanced Drug Delivery Reviews. Volume 160, 19-35. https://doi.org/10.1016/j.addr.2020.10.004. 
  • Francis, D.M., Manspeaker, M., Schudel, A., Sestito, L., O’Melia, M., Kissick, H., Pollack, B.P., Waller, E.K., Thomas, S.N.§, 2020. Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy. Science Translational Medicine. 12, eaay3575. 
  •  Sestito, L. and Thomas, S.N§. 2020. Lymph-directed nitric oxide increases immune cell access to lymph-borne nanoscale solutes. Biomaterials. doi.org/10.1016/j.biomaterials.2020.120411. 
  • Schudel, A., Chapman, A.P., Kwan, M.Y., Higgenson, C.J., Francis, D.M., Manspeaker, M.P., Avecilla, A.R.C., Rohner, N.A., Finn, M.G.§, Thomas, S.N.§, 2020. Programmable multistage delivery to lymph nodes. Nature Nanotechnology. https://doi.org/10.1038/s41565-020-0679-4. 
  • Cermeno, E., O’Melia, M., McDevitt, T., Lu, H., Huang, E., Thomas, S.N.§, Garcia, A.J.§, 2020. Hydrodynamic shear-based purification of cancer cells with enhanced tumorigenic potential. Integrative Biology. 12; 1–11. doi: 10.1093/intbio/zyz038. 
  •  Kim, J., Sestito, L., Im, S., Kim, W.J., Thomas, S.N.§, 2020. Poly(cyclodextrin)-Polydrug Nanocomplexes as Synthetic Oncolytic Virus for Locoregional Melanoma Chemoimmunotherapy. Advanced Functional Materials. 1908788. 
  • Kim, J., Manspeaker, M., Thomas, S.N.§, 2019. Augmenting the synergies of chemotherapy and immunotherapy through drug delivery. Acta Biomaterialia. pii: S1742-7061(19)30116-3. doi: 10.1016/j.actbio.2019.02.012
  • Palao-Suay R, Aguilar MR, Parra-Ruiz FJ, Maji S, Hoogenboom R, Rohner NA, Thomas SN, Román JS. 2016. α-Tocopheryl succinate-based amphiphilic block copolymers obtained by RAFT and their nanoparticles for the treatment of cancer. Polym Chem. 7(4):838-850. Epub 2015 Nov 27. PMID:27004068
  • Rohner NA, Thomas SN. 2016. Melanoma growth effects on molecular clearance from tumors and biodistribution into systemic tissues versus draining lymph nodes. J Control Release. 223:99-108. doi: 10.1016/j.jconrel.2015.12.027. Epub 2015 Dec 23. PMID:26721446
  • Oh J, Edwards EE, McClatchey PM, Thomas SN. 2015. Analytical cell adhesion chromatography reveals impaired persistence of metastatic cell rolling adhesion to P-selectin. J Cell Sci. 128(20):3731-43. doi: 10.1242/jcs.166439. Epub 2015 Sep 8. PMID:26349809
  • Rohner NA, McClain J, Tuell SL, Warner A, Smith B, Yun Y, Mohan A, Sushnitha M, Thomas SN. 2015. Lymph node biophysical remodeling is associated with melanoma lymphatic drainage. FASEB J. 29(11):4512-22. doi: 10.1096/fj.15-274761. Epub 2015 Jul 15. PMID:26178165

Eberhard Voit

  • Davis JD, Kumbale CM, Zhang Q, Voit EO. Dynamical systems approaches to personalized medicine. Curr Opin Biotechnol. 2019 Aug;58:168-174. doi: 10.1016/j.copbio.2019.03.005. Epub 2019 Apr 9. PMID: 30978644; PMCID: PMC7050596.
  • Qi Z, Voit EO. 2014. Identification of cancer mechanisms through computational systems modeling. Transl Cancer Res. 3(3):233-242. PMID:26662197

May Wang

  • Tong L, Wu H, and Wang MD. Integrating multi-omics data by learning modality invariant representations for improved prediction of overall survival of cancer. Methods. 2021. 189: 74-85. 
  • Tong L, Mitchel J, Chatlin K, and Wang MD. Deep Learning based feature-level integration of multi-omics data for breast cancer patients survival analysis. BMC Medical Informatics and Decision Making. 2020. 20: 225.
  • Tong L*, Wu PY*, Phan JH* (equal contribution first authors), Hassanzadeh HR, SEQC Consortium, Tong WD* and Wang MD* (co-corresponding senior author and handling author). Impact of RNA-seq data analysis algorithms on gene expression estimation and downstream prediction. Nature Scientific Reports. 10(1): 1-20. 2020.
  • Hassanzadeh, H, and Wang MD. An Integrated Deep Network for Cancer Survival Prediction Using Omics Data. Frontiers in big Data 4 (2021).
  • Kairdolf BA, Bouras A, Kaluzova M, Sharma AK, Wang MD, Hadjipanayis CG, Nie S. 2016. Intraoperative spectroscopy with ultrahigh sensitivity for image-guided surgery of malignant brain tumors. Anal Chem. 88(1):858-67. doi: 10.1021/acs.analchem.5b03453. Epub 2015 Dec 7. PMID:26587976

Ronghu Wu

  • Senhan Xu, Jiangnan Zheng, Haopeng Xiao, and Ronghu Wu. Simultaneously Identifying and Distinguishing Glycoproteins with O-GlcNAc and O-GalNAc (the Tn Antigen) in Human Cancer Cells. Analytical Chemistry 2022 94 (7), 3343-3351  DOI:10.1021/acs.analchem.1c05438.
  • Arhanti Sadanand, Victor Maximov, Jasmine Lee, Suttipong Suttapitugsakul, Jenny Shim, Chris Doering, Ronghu Wu, Robert Schnepp, Trent Spencer, Kelly Goldsmith. 2021. Proteomic profiling identifies PTK7 as a novel immunotherapeutic candidate for neuroblastoma. Can Res. 81, Supp 13:3034.
  • Chen W, Smeekens JM, Wu R. 2015. Systematic and site-specific analysis of N-sialoglycosylated proteins on the cell surface by integrating click chemistry and MS-based proteomics. Chemical Science, 6(8):4681-4689.
  • Chen W, Smeekens JM, Wu R. 2014. Comprehensive analysis of protein N-glycosylation sites by combining chemical deglycosylation with LC-MS. J Proteome Res. 13(3):1466-73. doi: 10.1021/pr401000c. Epub 2014 Feb 10.

Karen Abbott

  • Murali P, Johnson BP, Lu Z, Climer L, Scott, DA, Foulquier F, Oprea-Ilies G, Lupashin V, Drake RR, and Abbott KL (2020) Novel Role for the Golgi Membrane Protein TMEM165  in Control of Migration and Invasion for Breast Carcinoma. 2020; 11: 2747-2762. [PMID 32733646].
  • Guo H, Abbott KL. 2015. Functional impact of tumor-specific N-linked glycan changes in breast and ovarian cancers. Adv Cancer Res. 126:281-303.
  • Allam H, Aoki K, Benigno BB, McDonald JF, Mackintosh SG, Tiemeyer M, Abbott KL. 2015.  Glycomic analysis of membrane glycoproteins with bisecting glycosylation from ovarian cancer tissues reveals novel structures and functions. J Proteome Res. 14(1):434-46.
  • Dolezal S, Hester S, Kirby PS, Nairn A, Pierce M, Abbott KL. 2014. Elevated levels of glycophosphatidylinositol (GPI) anchored proteins in serum from human cancers detected by C. septicum alpha toxin. Cancer Biomark. 14(1):55-62.

Ravi Bellamkonda

  • Ravi V Bellamkonda, Anjana Jain, Nassir Mokarram-Dorri, Barun Brahma. 2022. Devices, systems, and methods for excavating cancer cells. US Patent number 11273250. 
  • Syed Faaiz Enam, Cem Y Kilic, Jianxi Huang, Brian J Kang, Reed Chen, Connor S Tribble, Martha I Betancur, Ekaterina Ilich, Stephanie J Blocker, Steven Owen, Johnathan G Lyon, Ravi V Bellamkonda. 2021. Cytostatic hypothermia and its impact on glioblastoma and survival. BioRxiv, Cold Spring Harbor Lab.
  • Tobey J MacDonald, Jingbo Liu, Bing Yu, Anshu Malhotra, Jenny Munson, Jaekeun C Park, Kenty Wang, Baowei Fei, Ravi Bellamkonda, Jack Arbiser. 2021. Liposome-imipramine blue inhibits sonic hedgehog medulloblastoma in vivo. Cancers 13:1220.
  • Johnathan G Lyon, Sheridan L Carroll, Nassir Mokarram, Ravi V Bellamkonda. 2019. Electrotaxis of glioblastoma and medulloblastoma speroidal aggregates. Sci Reports 9:1-19.

Benedict Benigno

  • Lanka, J, Housley, SN, Benigno, BB and McDonald, JF. (2021). ELAF: An ensemble-based machine learning algorithm that predicts anti-cancer drug response with high accuracy. J. Oncol. Res. 4 (1): 1-11.https://escires.com/articles/JOR-4-111.pdf
  • Stone, N.E., Raj, A., Young, K.M. , DeLuca, A.P., Chrit, F.E., Tucker, B.A., Alexeev, A., McDonald J.F., Benigno, B.B., Sulchek, T. (2021). Label-free microfluidic enrichment of cancer cells from non-cancer cells in ascites. Sci Rep 11, 18032. https://doi.org/10.1038/s41598-021-96862-y.

Nathan Bowen

  • Hewa Bostanthirige D, Komaragiri SK, Joshi JB, Alzahrani M, Saini I, Jain S, Bowen NJ, Havrda MC, Chaudhary J. The helix-loop-helix transcriptional regulator Id4 is required for terminal differentiation of luminal epithelial cells in the prostate. Oncoscience. 2021 Mar 24;8:14-30. doi: 10.18632/oncoscience.524. PMID: 33884281; PMCID: PMC8045964.
  • Dougan J, Hawsawi O, Burton LJ, Edwards G, Jones K, Zou J, Nagappan P, Wang G, Zhang Q, Danaher A, Bowen N, Hinton C, Odero-Marah VA. Proteomics-Metabolomics Combined Approach Identifies Peroxidasin as a Protector against Metabolic and Oxidative Stress in Prostate Cancer. Int J Mol Sci. 2019 Jun 21;20(12):3046. doi: 10.3390/ijms20123046. PMID: 31234468; PMCID: PMC6627806.
  • Burton LJ, Hawsawi O, Sweeney J, Bowen N, Hudson T, Odero-Marah V. CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-α) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE). PLoS One. 2019 Apr 9;14(4):e0214844. doi: 10.1371/journal.pone.0214844. PMID: 30964885; PMCID: PMC6460785.
  • Elliott B, Millena AC, Matyunina L, Zhang M, Zou J, Wang G, Zhang Q, Bowen N, Eaton V, Webb G, Thompson S, McDonald J, Khan S. Essential role of JunD in cell proliferation is mediated via MYC signaling in prostate cancer cells. Cancer Lett. 2019 Apr 28;448:155-167. doi: 10.1016/j.canlet.2019.02.005. Epub 2019 Feb 11. PMID: 30763715; PMCID: PMC6414252.
  • Sheng X, Bowen N, Wang Z. 2016. GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer.Mol Cancer. 2016 Mar 18;15(1):25. doi: 10.1186/s12943-016-0508-4. PMID:26988096
  • Du F, Li Y, Zhang W, Kale SP, McFerrin H, Davenport I, Wang G, Skripnikova E, Li XL, Bowen NJ, McDaniels LB, Meng YX, Polk P, Liu YY, Zhang QJ. 2016. Highly and moderately aggressive mouse ovarian cancer cell lines exhibit differential gene expression. Tumour Biol. 2016 Mar 2. [Epub ahead of print] PMID:26935058
  • Pannu V, Rida PC, Ogden A, Turaga RC, Donthamsetty S, Bowen NJ, Rudd K, Gupta MV, Reid MD, Cantuaria G, Walczak CE, Aneja R. 2015. HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patients. Oncotarget. 6(8):6076-91. PMID:25788277
  • Chinaranagari S, Sharma P, Bowen NJ, Chaudhary J. 2015. Prostate cancer epigenome. Methods Mol Biol. 1238:125-40. doi: 10.1007/978-1-4939-1804-1_7. PMID:25421658
  • Pawar S, Donthamsetty S, Pannu V, Rida P, Ogden A, Bowen N, Osan R, Cantuaria G, Aneja R. 2014. KIFCI, a novel putative prognostic biomarker for ovarian adenocarcinomas: delineating protein interaction networks and signaling circuitries. J Ovarian Res. 7:53. doi: 10.1186/1757-2215-7-53. eCollection 2014. PMID:25028599
  • Patel D, Knowell AE, Korang-Yeboah M, Sharma P, Joshi J, Glymph S, Chinaranagari S, Nagappan P, Palaniappan R, Bowen NJ, Chaudhary J. 2014. Inhibitor of differentiation 4 (ID4) inactivation promotes de novo steroidogenesis and castration-resistant prostate cancer. Mol Endocrinol. 2014 Aug;28(8):1239-53. doi: 10.1210/me.2014-1100. Epub 2014 Jun 12. PMID:24921661

Michael Pierce

  • Guo H, Nagy T, Pierce M. 2014. Post-translational glycoprotein modifications regulate colon cancer stem cells and colon adenoma progression in Apc(min/+) mice through altered Wnt receptor signaling. J Biol Chem. 289(45):31534-49. doi: 10.1074/jbc.M114.602680. Epub 2014 Oct 1. PMID:25274627
  • Dolezal S, Hester S, Kirby PS, Nairn A, Pierce M, Abbott KL. 2014. Elevated levels of glycosylphosphatidylinositol (GPI) anchored proteins in plasma from human cancers detected by C. septicum alpha toxin. Cancer Biomark. 14(1):55-62. doi: 10.3233/CBM-130377. PMID:24643042

Ricardo Alvarez

  • Huo L, Wang Y, Gong Y, Krishnamurthy S, Wang J, Diao L, Liu CG, Liu X, Lin F, Symmans WF, Wei W, Zhang X, Sun L, Alvarez RH, Ueno NT, Fouad TM, Harano K, Debeb BG, Wu Y, Reuben J, Cristofanilli M, Zuo Z. 2016.  MicroRNA expression profiling identifies decreased expression of miR-205 in inflammatory breast cancer. Mod Pathol. 29(4):330-46. doi: 10.1038/modpathol.2016.38. Epub 2016 Feb 26. PMID:26916073
  • Kogawa T, Fouad TM, Liu DD, Wu J, Shen Y, Masuda H, Fujii T, Chavez-MacGregor M, Alvarez RH, Hortobágyi GN, Valero V, Ueno NT. 2016. High HER2/Centromeric Probe for chromosome 17 fluorescence in situ hybridization ratio predicts pathologic complete response and survival outcome in patients receiving neoadjuvant systemic therapy with trastuzumab for her2 overexpressing locally advanced breast cancer. Oncologist. 21(1):21-7. doi: 10.1634/theoncologist.2015-0101. Epub 2015 Dec 9. PMID:26659222
  • Niu J, Andres G, Kramer K, Kundranda MN, Alvarez RH, Klimant E, Parikh AR, Tan B, Staren ED, Markman M. 2015.  Incidence and clinical significance of ESR1 mutations in heavily pretreated metastatic breast cancer patients. Onco Targets Ther. 2015 Nov 11;8:3323-8. doi: 10.2147/OTT.S92443. eCollection 2015. PMID:26648736
  • Roy-Chowdhuri S, de Melo Gagliato D, Routbort MJ, Patel KP, Singh RR, Broaddus R, Lazar AJ, Sahin A, Alvarez RH, Moulder S, Wheler JJ, Janku F, Gonzalez-Angulo AM, Chavez-MacGregor M, Valero V, Ueno NT, Mills G, Mendelsohn J, Yao H, Aldape K, Luthra R, Meric-Bernstam F. 2015. Multigene clinical mutational profiling of breast carcinoma using next-generation sequencing. Am J Clin Pathol. 2015 Nov;144(5):713-21. doi: 10.1309/AJCPWDEQYCYC92JQ. PMID:26486734
  • Fujii T, Le Du F, Xiao L, Kogawa T, Barcenas CH, Alvarez RH, Valero V, Shen Y, Ueno NT. 2015. Effectiveness of an adjuvant chemotherapy regimen for early-stage breast cancer: A systematic review and network meta-analysis. JAMA Oncol. 1(9):1311-8. doi: 10.1001/jamaoncol.2015.3062.  PMID:26402167
  • Fouad TM, Kogawa T, Liu DD, Shen Y, Masuda H, El-Zein R, Woodward WA, Chavez-MacGregor M, Alvarez RH, Arun B, Lucci A, Krishnamurthy S, Babiera G, Buchholz TA, Valero V, Ueno NT. 2015. Erratum to: Overall survival differences between patients with inflammatory and noninflammatory breast cancer presenting with distant metastasis at diagnosis. Breast Cancer Res Treat. 2015 Jul;152(2):417. doi: 10.1007/s10549-015-3477-1. PMID:26092296
  • Fouad TM, Kogawa T, Liu DD, Shen Y, Masuda H, El-Zein R, Woodward WA, Chavez-MacGregor M, Alvarez RH, Arun B, Lucci A, Krishnamurthy S, Babiera G, Buchholz TA, Valero V, Ueno NT. 2015.  Overall survival differences between patients with inflammatory and noninflammatory breast cancer presenting with distant metastasis at diagnosis. Breast Cancer Res Treat. 152(2):407-16. doi: 10.1007/s10549-015-3436-x. Epub 2015 May 29. Erratum in: Breast Cancer Res Treat. 2015 Jul;152(2):417.  PMID:26017070
  • Mitri Z, Karakas C, Wei C, Briones B, Simmons H, Ibrahim N, Alvarez R, Murray JL, Keyomarsi K, Moulder S. 2015. A phase 1 study with dose expansion of the CDK inhibitor dinaciclib (SCH 727965) in combination with epirubicin in patients with metastatic triple negative breast cancer. Invest New Drugs. 33(4):890-4. doi: 10.1007/s10637-015-0244-4. Epub 2015 May 7. PMID:25947565
  • Kogawa T, Fouad TM, Wei C, Masuda H, Kai K, Fujii T, El-Zein R, Chavez-MacGregor M, Litton JK, Brewster A, Alvarez RH, Hortobagyi GN, Valero V, Theriault R, Ueno NT. 2015.  Association of body mass index changes during neoadjuvant chemotherapy with pathologic complete response and clinical outcomes in patients with locally advanced breast cancer. J Cancer. 6(4):310-8. doi: 10.7150/jca.10580. eCollection 2015. PMID:25767600
  • Goswami RS, Patel KP, Singh RR, Meric-Bernstam F, Kopetz ES, Subbiah V, Alvarez RH, Davies MA, Jabbar KJ, Roy-Chowdhuri S, Lazar AJ, Medeiros LJ, Broaddus RR, Luthra R, Routbort MJ. 2015. Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors. Clin Cancer Res. 21(11):2644-51. doi: 10.1158/1078-0432.CCR-14-2391. Epub 2015 Feb 18. PMID:25695693
  • Mego M, Giordano A, De Giorgi U, Masuda H, Hsu L, Giuliano M, Fouad TM, Dawood S, Ueno NT, Valero V, Andreopoulou E, Alvarez RH, Woodward WA, Hortobagyi GN, Cristofanilli M, Reuben JM. 2015. Circulating tumor cells in newly diagnosed inflammatory breast cancer. Breast Cancer Res. 2015 Jan 9;17:2. doi: 10.1186/s13058-014-0507-6. PMID:25572591
  • Mego M, Zuo Z, Gao H, Cohen EN, Giordano A, Tin S, Anfossi S, Jackson S, Woodward W, Ueno NT, Valero V, Alvarez RH, Hortobagyi GN, Khoury JD, Cristofanilli M, Reuben JM. 2015. Circulating tumour cells are linked to plasma D-dimer levels in patients with metastatic breast cancer. Thromb Haemost. 2015 Mar;113(3):593-8. doi: 10.1160/TH14-07-0597. Epub 2014 Nov 6. PMID:25373787

Benedict Benigno

  • Benigno, B.B. 2016. The Ultimate Guide to Ovarian Cancer: Everything You Need to Know About Diagnosis, Treatment and Research, 2nd Edition. Sherryben Publishing House, LLC. Atlanta, GA
  • Gaul DA, Mezencev R, Long TQ, Jones CM, Benigno BB, Gray A, Fernández FM, McDonald JF. 2015. Highly-accurate metabolomic detection of early-stage ovarian cancer. Sci Rep. 5:16351. doi: 10.1038/srep16351. PMID:26573008
  • Allam H, Aoki K, Benigno BB, McDonald JF, Mackintosh SG, Tiemeyer M, Abbott KL. 2015. Glycomic analysis of membrane glycoproteins with bisecting glycosylation from ovarian cancer tissues reveals novel structures and functions. J Proteome Res. 14(1):434-46. doi: 10.1021/pr501174p. Epub 2014 Dec 9. PMID:25437919

Guilherme Cantuaria

  • Klopp AH, Yeung AR, Deshmukh S, Gil KM, Wenzel L, Westin SN, Gifford K, Gaffney DK, Small W Jr, Thompson S, Doncals DE, Cantuaria GHC, Yaremko BP, Chang A, Kundapur V, Mohan DS, Haas ML, Kim YB, Ferguson CL, Pugh SL, Kachnic LA, Bruner DW. Patient-Reported Toxicity During Pelvic Intensity-Modulated Radiation Therapy: NRG Oncology-RTOG 1203. J Clin Oncol. 2018 Aug 20;36(24):2538-2544. doi: 10.1200/JCO.2017.77.4273. Epub 2018 Jul 10. Erratum in: J Clin Oncol. 2019 Mar 20;37(9):761. Erratum in: J Clin Oncol. 2020 Apr 1;38(10):1118. PMID: 29989857; PMCID: PMC6097832.
  • Vergote I, Ray-Coquard I, Anderson DM, Cantuaria G, Colombo N, Garnier-Tixidre C, Gilbert L, Harter P, Hettle R, Lorusso D, Mäenpää J, Marth C, Matsumoto K, Ouwens M, Poveda A, Raspagliesi F, Rhodes K, Rubio Pérez MJ, Shapira-Frommer R, Shikama A, Sikorska M, Moore K, DiSilvestro P. Population-adjusted indirect treatment comparison of the SOLO1 and PAOLA-1/ENGOT-ov25 trials evaluating maintenance olaparib or bevacizumab or the combination of both in newly diagnosed, advanced BRCA-mutated ovarian cancer. Eur J Cancer. 2021 Nov;157:415-423. doi: 10.1016/j.ejca.2021.08.023. Epub 2021 Sep 28. PMID: 34597975.
  • Bhattarai S, Klimov S, Mittal K, Krishnamurti U, Li XB, Oprea-Ilies G, Wetherilt CS, Riaz A, Aleskandarany MA, Green AR, Ellis IO, Cantuaria G, Gupta M, Manne U, Agboola J, Baskovich B, Janssen EAM, Callagy G, Walsh EM, Mehta A, Dogra A, Shet T, Gajaria P, Traina T, Nggada HA, Omonisi A, Ahmed SA, Rakha EA, Rida P, Aneja R. Prognostic Role of Androgen Receptor in Triple Negative Breast Cancer: A Multi-Institutional Study. Cancers (Basel). 2019 Jul 17;11(7):995. doi: 10.3390/cancers11070995. PMID: 31319547; PMCID: PMC6678933.
  • Yeung AR, Pugh SL, Klopp AH, Gil KM, Wenzel L, Westin SN, Gaffney DK, Small W Jr, Thompson S, Doncals DE, Cantuaria GHC, Yaremko BP, Chang A, Kundapur V, Mohan DS, Haas ML, Kim YB, Ferguson CL, Deshmukh S, Bruner DW, Kachnic LA. Improvement in Patient-Reported Outcomes With Intensity-Modulated Radiotherapy (RT) Compared With Standard RT: A Report From the NRG Oncology RTOG 1203 Study. J Clin Oncol. 2020 May 20;38(15):1685-1692. doi: 10.1200/JCO.19.02381. Epub 2020 Feb 19. PMID: 32073955; PMCID: PMC7238486.
  • Pisu M, Rocque GB, Jackson BE, Kenzik KM, Sharma P, Williams CP, Kvale EA, Taylor RA, Williams GR, Azuero A, Li Y, Acemgil A, Martin MY, Demark-Wahnefried W, Turkman Y, Fouad M, Rocconi RP, Sullivan M, Cantuaria G, Partridge EE, Meneses K. Lay navigation across the cancer continuum for older cancer survivors: Equally beneficial for Black and White survivors? J Geriatr Oncol. 2019 Sep;10(5):779-786. doi: 10.1016/j.jgo.2018.10.013. Epub 2018 Oct 30. PMID: 30389494.
  • Gil KM, Pugh SL, Klopp AH, Yeung AR, Wenzel L, Westin SN, Gaffney DK, Small W Jr, Thompson S, Doncals DE, Cantuaria GHC, Yaremko BP, Chang A, Kundapur V, Mohan DS, Haas ML, Kim YB, Ferguson CL, Deshmukh S, Kachnic LA, Bruner DW. Expanded validation of the EPIC bowel and urinary domains for use in women with gynecologic cancer undergoing postoperative radiotherapy. Gynecol Oncol. 2019 Jul;154(1):183-188. doi: 10.1016/j.ygyno.2019.04.682. Epub 2019 May 16. PMID: 31104905; PMCID: PMC6918674.
  • Mittal K, Choi da H, Klimov S, Pawar S, Kaur R, Mitra AK, Gupta MV, Sams R, Cantuaria G, Rida PC, Aneja R. 2016. A centrosome clustering protein, KIFC1, predicts aggressive disease course in serous ovarian adenocarcinomas. J Ovarian Res. 9(1):17. doi: 10.1186/s13048-016-0224-0. PMID:26992853
  • Rida PC, Cantuaria G, Reid MD, Kucuk O, Aneja R. 2015. How to be good at being bad: centrosome amplification and mitotic propensity drive intratumoral heterogeneity. Cancer Metastasis Rev. 34(4):703-13. doi: 10.1007/s10555-015-9590-0. PMID:26358854
  • Pannu V, Mittal K, Cantuaria G, Reid MD, Li X, Donthamsetty S, McBride M, Klimov S, Osan R, Gupta MV, Rida PC, Aneja R. 2015. Rampant centrosome amplification underlies more aggressive disease course of triple negative breast cancers. Oncotarget. 6(12):10487-97. PMID:25868856
  • Pannu V, Rida PC, Ogden A, Turaga RC, Donthamsetty S, Bowen NJ, Rudd K, Gupta MV, Reid MD, Cantuaria G, Walczak CE, Aneja R. 2015. HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patients. Oncotarget. 6(8):6076-91. PMID:25788277

Michelle Dawson

  • Dawson M (2022). Special Issue: Molecular and Cellular Heterogeneity in an Evolving Tumor Landscape: When Diversity Gives Rise to Aggressive and Drug Resistant Cells. Cancers. Guest edited by Michelle Dawson 
  • Dawson M (2022). Engineering and Physical Approaches to Cancer. Book Series: Current Cancer Research. Springer Publishing. Co-Edited by Michelle Dawson and Ian Wong 
  • Lee AH, Koh IL, Dawson MR. 2022. The role of exosome heterogeneity in epithelial ovarian cancer. Adv in Can Biol - Metastasis. 4, 2022, 100040, ISSN 2667-3940,
  • https://doi.org/10.1016/j.adcanc.2022.100040.
  • Lee AH, Mejia Peña C, Dawson MR. Comparing the Secretomes of Chemorefractory and Chemoresistant Ovarian Cancer Cell Populations. Cancers. 2022; 14(6):1418. https://doi.org/10.3390/cancers14061418.
  • Botai Xuan, Deepraj Ghosh, Michelle R. Dawson, Contributions of the distinct biophysical phenotype of polyploidal giant cancer cells to cancer progression, Seminars in Cancer Biology, 10.1016/j.semcancer.2021.05.014, (2021).
  • Lee AH, Ghosh D, Quach N, Schroeder D, Dawson M (2020). Ovarian Cancer Exosomes Trigger Differential Biophysical Response in Tumor-Derived Fibroblasts. Scientific Reports 10 (1), 1-16. 
  • Dawson M, Xuan B, Hsu J, Ghosh D (2020). Force balancing ACT-IN the Tumor Microenvironment: Cytoskeletal Modifications in Cancer and Stromal Cells to Promote Malignancy. IRCMB: Actin Cytoskeleton in Cancer Progression and Metastasis – Part B Volume 356. Edited by Clement Thomas and Lorenzo Galluzzi, Elsevier Publishing 
  • Botai Xuan, Deepraj Ghosh, Joy Jiang, Rachelle Shao, and Michelle R. Dawson. 2020. Vimentin filaments drive migratory persistence in polyploidal cancer cells. PNAS, USA. 117:26756-26765.

Ciro Isidoro

  • Vidoni C, Ferraresi A, Esposito A, Maheshwari C, Dhanasekaran DN, Mollace V, Isidoro C. Calorie Restriction for Cancer Prevention and Therapy: Mechanisms, Expectations, and Efficacy. J Cancer Prev. 2021 Dec 30;26(4):224-236. doi: 10.15430/JCP.2021.26.4.224. PMID: 35047448; PMCID: PMC8749320.
  • Vidoni C, Ferraresi A, Secomandi E, Vallino L, Dhanasekaran DN, Isidoro C. Epigenetic targeting of autophagy for cancer prevention and treatment by natural compounds. Semin Cancer Biol. 2020 Nov;66:34-44. doi: 10.1016/j.semcancer.2019.04.006. Epub 2019 May 2. PMID: 31054926.
  • Salwa A, Ferraresi A, Chinthakindi M, Vallino L, Vidoni C, Dhanasekaran DN, Isidoro C. BECN1 and BRCA1 Deficiency Sensitizes Ovarian Cancer to Platinum Therapy and Confers Better Prognosis. Biomedicines. 2021 Feb 18;9(2):207. doi: 10.3390/biomedicines9020207. PMID: 33670664; PMCID: PMC7922320.
  • Ha JH, Jayaraman M, Yan M, Dhanasekaran P, Isidoro C, Song YS, Dhanasekaran DN. GNAi2/gip2-Regulated Transcriptome and Its Therapeutic Significance in Ovarian Cancer. Biomolecules. 2021 Aug 14;11(8):1211. doi: 10.3390/biom11081211. PMID: 34439877; PMCID: PMC8393559.
  • Ferraresi A, Esposito A, Girone C, Vallino L, Salwa A, Ghezzi I, Thongchot S, Vidoni C, Dhanasekaran DN, Isidoro C. Resveratrol Contrasts LPA-Induced Ovarian Cancer Cell Migration and Platinum Resistance by Rescuing Hedgehog-Mediated Autophagy. Cells. 2021 Nov 17;10(11):3213. doi: 10.3390/cells10113213. PMID: 34831435; PMCID: PMC8625920.
  • Thongchot S, Jamjuntra P, Therasakvichya S, Warnnissorn M, Ferraresi A, Thuwajit P, Isidoro C, Thuwajit C. Interleukin 8 released by cancer associated fibroblasts attenuates the autophagy and promotes the migration of ovarian cancer cells. Int J Oncol. 2021 May;58(5):14. doi: 10.3892/ijo.2021.5194. Epub 2021 Mar 2. PMID: 33649784; PMCID: PMC7949624.
  • Ha JH, Jayaraman M, Yan M, Dhanasekaran P, Isidoro C, Song YS, Dhanasekaran DN. Identification of GNA12-driven gene signatures and key signaling networks in ovarian cancer. Oncol Lett. 2021 Oct;22(4):719. doi: 10.3892/ol.2021.12980. Epub 2021 Aug 10. PMID: 34429759; PMCID: PMC8371953.
  • Tang H, Sebti S, Titone R, Zhou Y, Isidoro C, Ross TS, Hibshoosh H, Xiao G, Packer M, Xie Y, Levine B. 2015.  Decreased mRNA Expression in human breast cancer is associated with estrogen receptor-negative subtypes and poor prognosis. EBioMedicine. 2(3):255-263. PMID

Shafiq Khan 

  • Venugopal SV, Caggia S, Gambrell-Sanders D, Khan SA (2020). Differential roles and activation of mammalian target of rapamycin complexes 1 and 2 during cell migration in prostate cancer cells. Prostate 80:412-423. 
  •   
  • Caggia S, Tapadar S, Wu B, Venugopal SV, Garrett AS, Kumar A, Stiffend JS, Davis JS, Oyelere AK, Khan SA (2020) Small molecule inhibitors targeting Gαi2 protein attenuate migration of cancer cells. Cancers 12(6), 1631. 
  • Caggia S, Chunduri H, Millena AC, Perkins JN, Venugopal SV, Vo BT, Li C, Tu Y, Khan SA (2018) Novel role of Giα2 in cell migration and invasion: downstream of PI3-kinase/AKT and Rac1 activation in prostate cancer cells. Journal of Cellular Physiology 234: 802-815. 
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  • Elliott B, Millena AC, Matyunina L, Zhang M, Zou J, Wang G, Zhang Q, Bowen N, Eaton V, Webb G, Thompson S, McDonald J, Khan SA (2019). Essential role of JunD in cell proliferation is mediated via MYC signaling in prostate cancer cells. Cancer Letters 448: 155-167. 
  • Elliott B, Zackery DL, Eaton VA, Jones RT, Abebe F, Ragin CC, Khan SA (2018). Ethnic Differences in TGFβ signaling pathway may contribute to prostate cancer health disparity. Carcinogenesis, 39: 546–555.